Ldhb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ldhb
lactate dehydrogenase B
MGI:96763

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ldhb^tm1.2Choy/Ldhb^tm1.2Choy involves: 129S4/SvJae * C57BL/6	abnormal cochlear ganglion morphology	J:371573
	abnormal neuron mitochondrial morphology	J:371573
	decreased cochlear hair cell stereocilia number	J:371573
	decreased cochlear outer hair cell number	J:371573
	increased apoptosis	J:371573
	increased or absent threshold for auditory brainstem response	J:371573
	increased susceptibility to age-related hearing loss	J:371573
	type II spiral ligament fibrocyte degeneration	J:371573
	type IV spiral ligament fibrocyte degeneration	J:371573
Ldhb^{tm1b(KOMP)Wtsi}/Ldhb^{tm1b(KOMP)Wtsi} C57BL/6N-Ldhb^{tm1b(KOMP)Wtsi}/Wtsi	absent pinna reflex	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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