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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Itga6
integrin alpha 6
MGI:96605
27 phenotypes from 5 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Itga6Gt(LST045)Byg/Itga6Gt(LST045)Byg
involves: 129P2/OlaHsd
normal hearing/vestibular/ear phenotype J:142510
Itga6tm1Egl/Itga6tm1Egl
either: (involves: 129S2/SvPas * C57BL/6) or (involves: 129S2/SvPas * C57BL/6 * CD-1)
abnormal brain morphology J:79739
abnormal mouth morphology J:33712
abnormal neuronal precursor cell migration J:79739
abnormal retina nerve fiber layer morphology J:79739
abnormal skin condition J:33712
abnormal vitreous body morphology J:79739
disorganized cortical plate J:79739
perinatal lethality, complete penetrance J:33712
Itga6tm1Egl/Itga6tm1Egl
involves: 129S2/SvPas * C57BL/6
abnormal basement membrane morphology J:119018
abnormal cerebral cortex morphology J:119018
Itga6tm1Son/Itga6tm1Son
involves: 129P2/OlaHsd * FVB
abnormal lymph node morphology J:50235
abnormal T cell physiology J:50235
decreased T cell number J:50235
Itga6tm2.1Egl/Itga6tm2.1Egl
involves: C57BL/6
blistering J:204174
perinatal lethality, complete penetrance J:204174
Itga6tm2Egl/Itga6tm2Egl
Tg(Mpz-cre)26Mes/0
involves: C57BL/6 * FVB/NTac
abnormal axon morphology J:204174
abnormal myelination J:204174
abnormal Schwann cell physiology J:204174
abnormal sciatic nerve morphology J:204174
axon degeneration J:204174
decreased myelin sheath thickness J:204174
hypermyelination J:204174
increased myelin sheath thickness J:204174
normal mortality/aging J:204174
Itga6tm2Egl/Itga6tm2Egl
Tg(Tie1-cre)9Ref/0
involves: 129S1/Sv * 129X1/SvJ
abnormal tumor vascularization J:156496
increased angiogenesis J:156496
increased tumor growth/size J:156496

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory