Il1b Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il1b
interleukin 1 beta
MGI:96543

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Il1a^tm1Yiw/Il1a^tm1Yiw Il1b^tm1Yiw/Il1b^tm1Yiw involves: 129S1/Sv * 129X1/SvJ * BALB/c	impaired neutrophil recruitment	J:50775
Il1a^tm1Yiw/Il1a^tm1Yiw Il1b^tm1Yiw/Il1b^tm1Yiw involves: 129S1/Sv * 129X1/SvJ * C57BL/6	decreased circulating corticosterone level	J:47429
	decreased circulating interleukin-1 alpha level	J:47429
	decreased circulating interleukin-1 beta level	J:47429
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:165513
	decreased susceptibility to type IV hypersensitivity reaction	J:165513
	impaired febrile response	J:47429
Il1a^tm1Yiw/Il1a^tm1Yiw Il1b^tm1Yiw/Il1b^tm1Yiw Tg(KRT14-CASP1)1Miz/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	dermatitis	J:78602
Il18^tm1Aki/Il18^tm1Aki Il1b^tm1Dch/Il1b^tm1Dch involves: 129P2/OlaHsd * 129S2/SvPas	increased susceptibility to bacterial infection	J:112400

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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