25 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Iapptm1Sgm/Iapp+ involves: 129P2/OlaHsd	abnormal trabecular bone morphology	J:88964
	decreased bone mass	J:88964
	decreased bone mineral density	J:88964
	decreased compact bone thickness	J:88964
	increased bone resorption	J:88964
	increased osteoclast cell number	J:88964
Iapptm1Sgm/Iapptm1Sgm involves: 129P2/OlaHsd	abnormal trabecular bone morphology	J:88964
	decreased bone mineral density	J:88964
	decreased compact bone thickness	J:88964
	increased bone resorption	J:88964
	increased osteoclast cell number	J:88964
	osteoporosis	J:88964
Iapptm1Sgm/Iapptm1Sgm involves: 129P2/OlaHsd * C57BL/6	normal homeostasis/metabolism phenotype	J:50042
	improved glucose tolerance	J:50042
	increased body weight	J:50042
	increased circulating insulin level	J:50042
Tg(Ins2-Iapp)6Soel/Tg(Ins2-Iapp)6Soel involves: FVB/N	abnormal pancreatic islet morphology	J:130022
	decreased susceptibility to autoimmune diabetes	J:130022
Tg(Ins2-IAPP)L13Gjsc/0 FVB/N-Tg(Ins2-IAPP)L13Gjsc	abnormal homeostasis	J:142009
	abnormal pancreas physiology	J:142009
	abnormal pancreatic beta cell physiology	J:142009
	abnormal pancreatic islet morphology	J:142009
	decreased circulating insulin level	J:142009
	decreased insulin secretion	J:142009
	decreased pancreatic beta cell mass	J:142009
	decreased pancreatic beta cell number	J:142009
	hyperglycemia	J:142009
	impaired glucose tolerance	J:142009
	increased amylin secretion	J:142009
	increased circulating glucagon level	J:142009
	increased pancreatic beta cell apoptosis	J:142009