H2-DMa Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-DMa
histocompatibility 2, class II, locus DMa
MGI:95921

8 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd74^tm1Doi/Cd74^tm1Doi H2-DMa^tm1Doi/H2-DMa^tm1Doi involves: 129S2/SvPas * C57BL/6	abnormal professional antigen presenting cell physiology	J:42482
	decreased body size	J:42482
	decreased CD4-positive, alpha-beta T cell number	J:42482
	increased CD8-positive, alpha-beta T cell number	J:42482
	premature death	J:42482
Cd74^tm1Liz/Cd74^tm1Liz H2-DMa^tm1Liz/H2-DMa^tm1Liz involves: 129S/SvEv * BALB/c	decreased CD4-positive, alpha-beta T cell number	J:113714
Cd74^tm1Liz/Cd74^tm1Liz H2-DMa^tm1Luc/H2-DMa^tm1Luc Tg(CD74)AR194Ayr/? involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J	abnormal antigen presentation via MHC class II	J:88717
	decreased CD4-positive, alpha-beta T cell number	J:88717
Cd74^tm1Liz/Cd74^tm1Liz H2-DMa^tm1Luc/H2-DMa^tm1Luc Tg(CD74)1Ayr/0 involves: 129S/SvEv 129S4/SvJae * C57BL/6J * DBA/2J	abnormal antigen presentation via MHC class II	J:88717
	decreased CD4-positive, alpha-beta T cell number	J:88717
H2-DMa^tm1Luc/H2-DMa^tm1Luc Cd74^tm1Doi/Cd74^tm1Doi involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	abnormal level of surface class II molecules	J:45185
	increased susceptibility to parasitic infection	J:45185

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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