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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Gsn
gelsolin
MGI:95851
28 phenotypes from 1 allele in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Gsntm1Djk/Gsntm1Djk
either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
abnormal bone remodeling J:60625
abnormal immune system physiology J:24346
abnormal long bone diaphysis morphology J:60625
abnormal long bone epiphyseal plate morphology J:60625
abnormal osteoclast differentiation J:60625
abnormal osteoclast physiology J:60625
abnormal platelet activation J:24346
abnormal skeleton morphology J:60625
abnormal skeleton physiology J:60625
abnormal wound healing J:24346
decreased inflammatory response J:24346
impaired neutrophil chemotaxis J:24346
impaired neutrophil recruitment J:24346
increased bleeding time J:24346
increased compact bone thickness J:60625
increased leukocyte cell number J:24346
increased neutrophil cell number J:24346
osteopetrosis J:60625
premature death J:52545
Gsntm1Djk/Gsntm1Djk
involves: 129S4/SvJae * BALB/c
abnormal branching of the mammary ductal tree J:64868
abnormal mammary duct terminal end bud morphology J:64868
abnormal mammary gland growth during pregnancy J:64868
lethality throughout fetal growth and development, complete penetrance J:64868
Gsntm1Djk/Gsntm1Djk
involves: 129S4/SvJae * C57BL/6
abnormal nervous system electrophysiology J:52545
abnormal pulmonary circulation J:94614
increased cerebral infarct size J:52545
increased susceptibility to ischemic brain injury J:52545
increased vascular permeability J:94614

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory