Gsx2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gsx2
GS homeobox 2
MGI:95843

21 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1^tm1(cre)Krj/Emx1⁺ Gsx2^tm2.1Kc/Gsx2^tm2.1Kc involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal lateral ganglionic eminence morphology	J:154936
	abnormal neuron differentiation	J:154936
	abnormal olfactory bulb morphology	J:154936
Gsx2^tm1.1Kc/Gsx2^tm1.1Kc involves: 129S6/SvEvTac * C57BL/6 * SJL	abnormal brain development	J:147161
Gsx2^tm1Ssp/Gsx2^tm1Ssp involves: 129	abnormal brain interneuron morphology	J:147161
Gsx2^tm1Ssp/Gsx2^tm1Ssp involves: 129	abnormal olfactory sensory neuron morphology	J:147161
Gsx2^tm1Ssp/Gsx2^tm1Ssp involves: 129S2/SvPas	abnormal area postrema morphology	J:44324
	abnormal forebrain development	J:44324
	abnormal fourth ventricle morphology	J:44324
	abnormal hindbrain development	J:44324
	abnormal lateral ganglionic eminence morphology	J:44324
	abnormal ventral striatum morphology	J:72724
	absent gastric milk in neonates	J:44324
	apnea	J:44324
	cyanosis	J:44324
	decreased striatum size	J:72724
	normal endocrine/exocrine gland phenotype	J:44324
	hypoxia	J:44324
	neonatal lethality, complete penetrance	J:44324
Gsx2^tm2.1Kc/Gsx2^tm2.1Kc involves: 129S6/SvEvTac * C57BL/6 * SJL	no abnormal phenotype detected	J:154936
Gsx2^tm2.2Kc/Gsx2^tm2.2Kc involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	abnormal neuron differentiation	J:154936
	abnormal telencephalon development	J:154936
	abnormal telencephalon morphology	J:154936
	decreased striatum size	J:154936

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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