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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Grin2c
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
MGI:95822
17 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cacna1atm1Kano/Cacna1atm1Kano
Grin2ctm2(icre)Mwa/Grin2c+
involves: C57BL/6N 		normal nervous system phenotype J:180582
Grin2atm1Mim/Grin2atm1Mim
Grin2ctm1Mwa/Grin2ctm1Mwa
involves: C57BL/6 * CBA 		abnormal motor coordination/balance J:92648
Grin2atm1Nak/Grin2atm1Nak
Grin2ctm1Nak/Grin2ctm1Nak
involves: 129S/SvEv 		abnormal excitatory postsynaptic currents J:66455
abnormal miniature excitatory postsynaptic currents J:66455
normal behavior/neurological phenotype J:66455
decreased vertical activity J:66455
impaired balance J:66455
normal nervous system phenotype J:66455
Grin2atm1Rsp/Grin2atm1Rsp
Grin2ctm1Rsp/Grin2ctm1Rsp
involves: 129S1/Sv * 129X1/SvJ 		impaired contextual conditioning behavior J:45446
impaired coordination J:45446
normal nervous system phenotype J:45446
Grin2btm1Mony/Grin2btm1Mony
Tg(Camk2a-Grin2c/itTA)12Rsp/0
Tg(tetO-cre)LC1Bjd/0
involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 		abnormal excitatory postsynaptic currents J:186311
abnormal NMDA-mediated synaptic currents J:186311
abnormal spatial learning J:186311
abnormal spatial working memory J:186311
normal behavior/neurological phenotype J:186311
decreased anxiety-related response J:186311
hyperactivity J:186311
Grin2ctm1(Grin2b)Ulme/Grin2ctm1(Grin2b)Ulme
involves: 129X1/SvJ * C57BL/6 		abnormal cerebellar molecular layer J:94369
impaired coordination J:94369
thin cerebellar granule layer J:94369
thin cerebellar molecular layer J:94369
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory