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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gas1
growth arrest specific 1
MGI:95655
66 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Boctm1Aok/Boc+
Gas1tm2Fan/Gas1+
involves: 129 * C57BL/6 * CD-1 		normal craniofacial phenotype J:310333
Boctm1Aok/Boc+
Gas1tm2Fan/Gas1tm2Fan
involves: 129 * C57BL/6 * CD-1 		abnormal palatal mesenchymal cell proliferation J:310333
abnormal secondary palate development J:310333
cleft palate J:310333
holoprosencephaly J:310333
Boctm1Aok/Boctm1Aok
Gas1tm2Fan/Gas1tm2Fan
involves: 129 * C57BL/6 * CD-1 		abnormal palatal mesenchymal cell proliferation J:310333
abnormal secondary palate development J:310333
abnormal vomeronasal organ morphology J:310333
bifid tongue J:310333
cleft palate J:310333
cleft secondary palate J:310333
failure of palatal shelf elevation J:310333
Cdontm2Rsk/Cdon+
Gas1tm2Fan/Gas1tm2Fan
involves: 129 * C57BL/6J 		hindlimb oligodactyly J:121553
syndactyly J:121553
Cdontm2Rsk/Cdontm2Rsk
Gas1tm2Fan/Gas1+
involves: 129 * C57BL/6J 		abnormal vertebral body morphology J:121553
hindlimb oligodactyly J:121553
syndactyly J:121553
Cdontm2Rsk/Cdontm2Rsk
Gas1tm2Fan/Gas1tm2Fan
involves: 129 * C57BL/6J 		abnormal craniofacial morphology J:121553
abnormal face development J:121553
abnormal limb morphology J:121553
abnormal nose morphology J:121553
abnormal vertebrae morphology J:121553
abnormal vertebral body morphology J:121553
absent mandible J:121553
absent maxilla J:121553
cervical vertebral fusion J:121553
holoprosencephaly J:121553
Gas1tm1Fan/Gas1tm1Fan
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal basisphenoid bone morphology J:122159
abnormal craniofacial bone morphology J:122159
abnormal incisor morphology J:122159
abnormal lower incisor morphology J:122159
abnormal mandible morphology J:122159
abnormal Meckel's cartilage morphology J:122159
abnormal middle ear morphology J:122159
abnormal molar morphology J:122159
abnormal nasal capsule morphology J:122159
abnormal neurocranium morphology J:122159
abnormal premaxilla morphology J:122159
abnormal stapes morphology J:122159
abnormal temporal bone morphology J:122159
absent gonial bone J:122159
absent incus J:122159
absent malleus J:122159
absent mandibular symphysis J:122159
absent tympanic ring J:122159
alisphenoid bone hypoplasia J:122159
cleft secondary palate J:122159
holoprosencephaly J:122159
perinatal lethality, complete penetrance J:122159
premature coronal suture closure J:122159
premaxilla hypoplasia J:122159
short Meckel's cartilage J:122159
single external naris J:122159
small cranium J:122159
synostosis J:122159
Gas1tm1Fan/Gas1tm1Fan
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal craniofacial morphology J:122159
embryonic lethality, complete penetrance J:122159
Gas1tm1Fan/Gas1tm1Fan
Vax1tm1Pgr/Vax1tm1Pgr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		absent upper incisors J:257247
Gas1tm2Fan/Gas1+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		increased neuronal precursor cell number J:121553
Gas1tm2Fan/Gas1tm2Fan
Gli3Xt-J/Gli3Xt-J
involves: 129/Sv * C3H/HeJ * C57BL/6J 		polydactyly J:121554
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shh+
involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		holoprosencephaly J:121554
oligodactyly J:121554
single external naris J:121554
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal craniofacial morphology J:121553
abnormal floor plate morphology J:121553
abnormal innervation J:121553
abnormal intervertebral disk morphology J:121553
abnormal nose morphology J:121553
abnormal vertebral body morphology J:121553
decreased fetal size J:121553
decreased neuronal precursor cell number J:121553
forelimb oligodactyly J:121553
short mandible J:121553
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shhtm1Chg
involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal embryo turning J:121554
abnormal heart tube morphology J:121554
abnormal rostral-caudal body axis extension J:121554
cardiac edema J:121554
decreased embryo size J:121554
embryonic growth arrest J:121554
embryonic lethality during organogenesis, complete penetrance J:121554
enlarged pericardium J:121554
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory