Fcgr2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fcgr2b
Fc receptor, IgG, low affinity IIb
MGI:95499

41 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fcgr2b^tm1.1Jsv/Fcgr2b^tm1.1Jsv involves: C57BL/6 * FVB/N	no abnormal phenotype detected	J:179175
Fcgr2b^tm1.2Rav/Fcgr2b^tm1.2Rav involves: C57BL/6	normal skeleton phenotype	J:197378
Fcgr2b^tm1Kgcs/Fcgr2b⁺ involves: C57BL/6	decreased B cell apoptosis	J:190890
	increased anti-chromatin antibody level	J:190890
	increased anti-double stranded DNA antibody level	J:190890
	increased germinal center B cell number	J:190890
	increased IgG1 level	J:190890
	increased IgG3 level	J:190890
	increased IgM level	J:190890
	increased susceptibility to induced arthritis	J:190890
	renal glomerular protein deposits	J:190890
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk B6.129S4-Fcgr2b^tm1Ttk	abnormal hypersensitivity reaction	J:64152
	abnormal seizure response to electrical stimulation	J:169028
	anemia	J:64152
	decreased body weight	J:64152
	dehydration	J:64152
	edema	J:64152
	enlarged lymph nodes	J:64152
	enlarged spleen	J:64152
	glomerulonephritis	J:64152
	hunched posture	J:64152
	increased immunoglobulin level	J:64152
	increased inflammatory response	J:64152
	increased urine protein level	J:64152
	kidney inflammation	J:64152
	liver inflammation	J:64152
	lung inflammation	J:64152
	maximal tonic hindlimb extension seizures	J:169028
	pancreas inflammation	J:64152
	premature death	J:64152
	salivary gland inflammation	J:64152
	tonic-clonic seizures	J:169028
	vascular inflammation	J:64152
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk C.129S4-Fcgr2b^tm1Ttk	decreased susceptibility to parasitic infection	J:120905
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk C.129S4-Fcgr2b^tm1Ttk	normal mortality/aging	J:64152
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk involves: 129S4/SvJae	abnormal mast cell physiology	J:31133
	increased IgA level	J:31133
	increased IgG1 level	J:31133
	increased IgG2a level	J:31133
	increased IgG2b level	J:31133
	increased IgG3 level	J:31133
	increased IgG level	J:31133
	increased IgM level	J:31133
	increased susceptibility to type I hypersensitivity reaction	J:31133
Fcgr2b^tm1Ttk/Fcgr2b^tm1Ttk Not Specified	increased susceptibility to induced arthritis	J:106191

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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