Cacnb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
MGI:894644

26 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cacnb2^tm1.1Mfre/Cacnb2^tm1.1Mfre Tg(CAG-Bgeo/GFP)21Lbe/? involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N	abnormal cardiovascular system morphology	J:126506
	abnormal cardiovascular system physiology	J:126506
	abnormal face development	J:126506
	abnormal heart development	J:126506
	abnormal heart looping	J:126506
	abnormal heart tube morphology	J:126506
	abnormal myocardial fiber physiology	J:126506
	abnormal vitelline vascular remodeling	J:126506
	decreased cardiac output	J:126506
	decreased heart rate	J:126506
	decreased hemangioblast number	J:126506
	delayed brain development	J:126506
	embryonic growth retardation	J:126506
	embryonic lethality during organogenesis, complete penetrance	J:126506
	hemorrhage	J:126506
	pale yolk sac	J:126506
	pericardial effusion	J:126506
	thin myocardium	J:126506
Cacnb2^tm1Rgg/Cacnb2^tm1Rgg Pde6b^rd1/Pde6b^rd1 Tg(Myh6-Cacnb2)1Rgg/0 involves: 129S7/SvEvBrd * C57BL/6J * FVB	abnormal cone electrophysiology	J:80080
	abnormal eye electrophysiology	J:80080
	abnormal eye physiology	J:80080
	decreased retina photoreceptor cell number	J:79923
	disorganized retina outer plexiform layer	J:80080
	retina photoreceptor degeneration	J:79923
	thin retina outer nuclear layer	J:79923
	thin retina outer plexiform layer	J:80080

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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