Cacnb2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
MGI:894644

10 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cacnb2^{tm1.1(KOMP)Vlcg}/Cacnb2^{tm1.1(KOMP)Vlcg} C57BL/6N-Cacnb2^{tm1.1(KOMP)Vlcg}/Tcp	abnormal urinary bladder morphology	J:211773
	impaired glucose tolerance	J:211773
	increased circulating glucose level	J:211773
Cacnb2^tm1Mfre/Cacnb2^tm1.1Mfre Myl2^tm1(cre)Krc/Myl2⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6N * FVB/N	abnormal myocardial fiber physiology	J:126506
	abnormal vitelline vascular remodeling	J:126506
	decreased heart rate	J:126506
	embryonic lethality during organogenesis, complete penetrance	J:126506
Cacnb2^tm1Rgg/Cacnb2^tm1Rgg involves: 129S7/SvEvBrd	abnormal cardiovascular system physiology	J:80080
Cacnb2^tm1Rgg/Cacnb2^tm1Rgg involves: 129S7/SvEvBrd	embryonic lethality, complete penetrance	J:80080
Cacnb2^tm1Rgg/Cacnb2^tm1Rgg involves: 129S7/SvEvBrd * FVB	normal vision/eye phenotype	J:136113

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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