Prap1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prap1
proline-rich acidic protein 1
MGI:893573

14 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prap1^tm1Lex/Prap1^tm1Lex B6.129S5-Prap1^tm1Lex	abnormal cell cycle	J:304152
	abnormal enterocyte physiology	J:304152
	abnormal gut flora balance	J:304152
	abnormal response to radiation	J:304152
	increased cellular sensitivity to ionizing radiation	J:304152
	increased circulating interleukin-2 level	J:304152
	increased circulating interleukin-4 level	J:304152
	increased circulating interleukin-12 level	J:304152
	increased enterocyte apoptosis	J:304152
	increased inflammatory response	J:304152
	increased interleukin-12b secretion	J:304152
	increased mortality induced by ionizing radiation	J:304152
Prap1^tm1Lex/Prap1^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	abnormal humoral immune response	J:171883
	increased immunoglobulin level	J:171883

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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