Comt Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Comt
catechol-O-methyltransferase
MGI:88470

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Comt^{tm1(COMT)Xzho}/Comt^{tm1(COMT)Xzho} involves: 129 * C57BL/6J	abnormal spatial working memory	J:224284
	normal behavior/neurological phenotype	J:224284
	decreased prepulse inhibition	J:224284
	decreased vertical activity	J:224284
	enhanced contextual conditioning behavior	J:224284
	impaired cued conditioning behavior	J:224284
	increased prepulse inhibition	J:224284
	increased startle reflex	J:224284
Comt^{tm2(COMT)Xzho}/Comt^{tm2(COMT)Xzho} involves: 129 * C57BL/6J	abnormal fear-related response	J:224284
	abnormal spatial working memory	J:224284
	normal behavior/neurological phenotype	J:224284
	decreased prepulse inhibition	J:224284
	decreased startle reflex	J:224284
	enhanced cued conditioning behavior	J:224284
	impaired contextual conditioning behavior	J:224284
	increased prepulse inhibition	J:224284
	increased vertical activity	J:224284

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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