F8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F8
coagulation factor VIII
MGI:88383

8 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F8^tm1.1Len/Y B6.Cg-F8^tm1.1Len	abnormal immune tolerance	J:266699
	impaired blood coagulation	J:266699
	postnatal lethality, incomplete penetrance	J:266699
F8^tm1.1Rmnt/F8^tm1.1Rmnt Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca * SJL	decreased circulating factor VIII level	J:212401
F8^tm1.1Rmnt/F8^tm1.1Rmnt Tg(Cdh5-cre)7Mlia/0 involves: 129 * C57BL/6 * FVB/N * SJL	decreased circulating factor VIII level	J:212401
F8^tm1.1Rmnt/F8^tm1.1Rmnt Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	decreased circulating factor VIII level	J:212401
F8^tm1Kaz/Y involves: 129S4/SvJae * C57BL/6	abnormal immune tolerance	J:178969, J:266699
	normal hematopoietic system phenotype	J:24941, J:36698
	impaired blood coagulation	J:24941, J:36698, J:266699
	increased susceptibility to induced morbidity/mortality	J:24941, J:36698
F8^tm1Kaz/F8^tm1Kaz involves: 129S4/SvJae * C57BL/6	normal hematopoietic system phenotype	J:36698
	impaired blood coagulation	J:36698
	increased susceptibility to induced morbidity/mortality	J:36698
	normal reproductive system phenotype	J:36698
F8^tm2Kaz/Y involves: 129S4/SvJae	abnormal blood coagulation	J:176909
F8^tm2Kaz/Y involves: 129S4/SvJae * C57BL/6	abnormal blood coagulation	J:24941, J:36698

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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