F8 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F8
coagulation factor VIII
MGI:88383

6 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F8^tm1.1Rmnt/F8^tm1.1Rmnt Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca * SJL	decreased circulating factor VIII level	J:212401
F8^tm1.1Rmnt/F8^tm1.1Rmnt Tg(Cdh5-cre)7Mlia/0 involves: 129 * C57BL/6 * FVB/N * SJL	decreased circulating factor VIII level	J:212401
F8^tm1.1Rmnt/F8^tm1.1Rmnt Tg(Tek-cre)1Ywa/0 involves: 129 * C57BL/6 * SJL	decreased circulating factor VIII level	J:212401
F8^tm1Kaz/Y involves: 129S4/SvJae * C57BL/6	abnormal blood coagulation	J:24941, J:36698
	abnormal immune tolerance	J:178969
	normal hematopoietic system phenotype	J:24941, J:36698
	increased susceptibility to induced morbidity/mortality	J:24941, J:36698
F8^tm1Kaz/F8^tm1Kaz involves: 129S4/SvJae * C57BL/6	abnormal blood coagulation	J:36698
	normal hematopoietic system phenotype	J:36698
	increased susceptibility to induced morbidity/mortality	J:36698
	normal reproductive system phenotype	J:36698
F8^tm2Kaz/Y involves: 129S4/SvJae	abnormal blood coagulation	J:176909
F8^tm2Kaz/Y involves: 129S4/SvJae * C57BL/6	abnormal blood coagulation	J:24941, J:36698

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23