Apoa2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apoa2
apolipoprotein A-II
MGI:88050

14 phenotypes from 5 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apoa2^a/Apoa2^a SAMP3	amyloidosis	J:11543
Apoa2^b/? involves: KK * RR	increased circulating cholesterol level	J:99474
Apoa2^b/Apoa2^b SAMP6	amyloidosis	J:11543
Apoa2^c/Apoa2^c SAMP7	amyloidosis	J:11543
Apoa2^c/Apoa2^c SAMP9	amyloidosis	J:11543
Apoa2^tm1Bres/Apoa2^tm1Bres involves: 129S4/SvJae	abnormal cholesterol homeostasis	J:37250
	decreased circulating cholesterol level	J:37250
	decreased circulating free fatty acids level	J:37250
	decreased circulating glucose level	J:37250
	decreased circulating HDL cholesterol level	J:37250
	decreased circulating insulin level	J:37250
Tg(Apoa2)1Lus/? involves: C57BL/6J * DBA/2	abnormal lipid homeostasis	J:92454, J:127063
	atherosclerotic lesions	J:127063
	increased circulating cholesterol level	J:92454, J:127063
	increased circulating HDL cholesterol level	J:92454, J:127063
	increased circulating LDL cholesterol level	J:92454
	increased circulating triglyceride level	J:92454
	increased circulating VLDL cholesterol level	J:92454

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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