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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Agrn
agrin
MGI:87961
35 phenotypes from 8 alleles in 12 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal neuromuscular synapse morphology J:70273
neonatal lethality, complete penetrance J:70273
normal renal/urinary system phenotype J:122821
Agrnnmf380/Agrnnmf380
C57BL/6J-Agrnnmf380/J 		abnormal hindlimb morphology J:176117
abnormal motor capabilities/coordination/movement J:176117
abnormal neuromuscular synapse morphology J:176117
abnormal skeletal muscle fiber type ratio J:176117
camptodactyly J:87349
decreased body size J:87349, J:176117
impaired limb coordination J:87349
limb grasping J:87349
muscle spasm J:87349
myopathy J:87349
normal nervous system phenotype J:176117
paraparesis J:87349
premature death J:176117
skeletal muscle atrophy J:176117
tremors J:87349
Agrnnmf380/Agrnnmf380
involves: BALB/c * C57BL/6J 		abnormal neuromuscular synapse morphology J:176117
premature death J:176117
Agrnnmf380/Agrnnmf380
involves: C57BL/6J * CAST 		abnormal neuromuscular synapse morphology J:176117
normal mortality/aging J:176117
normal muscle phenotype J:176117
Agrnnmf380/Agrnnmf380
involves: C57BL/6J * DBA 		abnormal neuromuscular synapse morphology J:176117
premature death J:176117
skeletal muscle atrophy J:176117
Agrnnmf380/Agrnnmf380
involves: C57BL/6J * FVB/N 		abnormal neuromuscular synapse morphology J:176117
premature death J:176117
Agrntm1Jrs/Agrntm1Jrs
involves: 129S1/Sv * 129X1/SvJ 		abnormal axon morphology J:33098
abnormal innervation J:33098
abnormal innervation pattern to muscle J:33098
abnormal neuromuscular synapse morphology J:33098
abnormal paired-pulse inhibition J:79028
decreased CNS synapse formation J:79028
increased post-tetanic potentiation J:79028
perinatal lethality, complete penetrance J:33098
Agrntm1Jrs/Agrntm1Jrs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		neonatal lethality J:55407
normal nervous system phenotype J:55407
Agrntm1Rwb/Agrntm1Rwb
Tg(NPHS2-cre)295Lbh/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal renal glomerulus basement membrane morphology J:122821
increased renal glomerulus basement membrane thickness J:122821
normal renal/urinary system phenotype J:122821
Agrntm1Rwb/Agrntm1Rwb
Tg(Pax3-cre)1Joe/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal diaphragm morphology J:122821
abnormal neuromuscular synapse morphology J:122821
perinatal lethality, complete penetrance J:122821
Agrntm1Rwb/Agrntm1Rwb
Tg(Tek-cre)1Ywa/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal blood vessel morphology J:220073
normal nervous system phenotype J:220073
Agrntm2Jrs/Agrntm2Jrs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		no abnormal phenotype detected J:55407
Agrntm3Jrs/Agrntm3Jrs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal innervation J:55407
abnormal neuromuscular synapse morphology J:55407
no spontaneous movement J:55407
perinatal lethality, complete penetrance J:55407
primary atelectasis J:55407
Agrntm4Jrs/Agrntm4Jrs
involves: 129 * C57BL/6 		normal renal/urinary system phenotype J:122821
Agrntm4Jrs/Agrntm4Jrs
Not Specified 		failure of neuromuscular synapse presynaptic differentiation J:161300
Agrntm5Jrs/Agrntm5Jrs
involves: 129S1/Sv * 129X1/SvJ * FVB/N 		normal mortality/aging J:220073
normal nervous system phenotype J:220073
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory