Rr28 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rr28
regulatory region 28
MGI:5489791

29 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Rr28^tm1Tilg/Rr28⁺ Igf2^tm1Rob/Igf2⁺ involves: 129S/SvEv * 129S1/Sv * C57BL/6J	abnormal circulating hormone level	J:77413
	abnormal fetal cardiomyocyte proliferation	J:77413
	abnormal heart septum morphology	J:77413
	abnormal heart ventricle morphology	J:77413
	abnormal lens development	J:77413
	abnormal lens epithelium morphology	J:77413
	abnormal lumbar vertebrae morphology	J:77413
	abnormal myocardium layer morphology	J:77413
	adrenal gland cyst	J:77413
	cleft palate	J:77413
	decreased kidney weight	J:77413
	delayed eyelid fusion	J:77413
	edema	J:77413
	enlarged aortic valve	J:77413
	enlarged pulmonary valve	J:77413
	increased fetal weight	J:77413
	increased heart weight	J:77413
	increased hepatocyte proliferation	J:77413
	increased liver weight	J:77413
	increased placenta weight	J:77413
	lethality throughout fetal growth and development, complete penetrance	J:77413
	omphalocele	J:77413
	pericardial edema	J:77413
	polydactyly	J:77413
	split sternum	J:77413
	thick aortic valve	J:77413
	thick pulmonary valve	J:77413
Rr28^tm1Tilg/Rr28⁺ Igf2^tm1Rob/Igf2⁺ Igf2r^tm1Stw/Igf2r⁺ involves: 129S/SvEv * 129S1/Sv * C57BL/6J	increased fetal weight	J:77413
	neonatal lethality, complete penetrance	J:77413
	polydactyly	J:77413
Rr28^tm1Tilg/Rr28⁺ Tg(CRP-TAg)60-3Urt/0 involves: 129S1/Sv * C57BL/6 * SJL	increased liver tumor incidence	J:138826

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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