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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
n-TUtca2
nuclear encoded tRNA selenocysteine 2 (anticodon TCA)
MGI:4414022
41 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
n-TUtca2tm1.1Dhat/n-TUtca2tm1.1Dhat
involves: FVB/N
prenatal lethality, complete penetrance J:82321
n-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Col2a1-cre)1Bhr/0
B6.Cg-n-TUtca2tm1Dhat Tg(Col2a1-cre)1Bhr
abnormal bone mineralization J:152152
abnormal cartilage morphology J:152152
abnormal craniofacial development J:152152
abnormal cranium morphology J:152152
abnormal frontal bone morphology J:152152
abnormal jaw morphology J:152152
abnormal limb morphology J:152152
abnormal long bone epiphyseal plate morphology J:152152
abnormal long bone epiphyseal plate proliferative zone J:152152
abnormal lumbar vertebrae morphology J:152152
abnormal neurocranium morphology J:152152
abnormal skeleton morphology J:152152
abnormal skeleton physiology J:152152
abnormal tracheal cartilage morphology J:152152
abnormal vertebrae morphology J:152152
decreased body length J:152152
decreased body size J:152152
decreased length of long bones J:152152
delayed bone ossification J:152152
frontal bossing J:152152
increased long bone epiphyseal plate size J:152152
increased width of hypertrophic chondrocyte zone J:152152
microcephaly J:152152
outer ear hypoplasia J:152152
postnatal growth retardation J:152152
premature death J:152152
short limbs J:152152
short snout J:152152
short tail J:152152
small cranium J:152152
trachea stenosis J:152152
tracheomalacia J:152152
n-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(MMTV-cre)4Mam/0
involves: 129 * C57BL/6 * FVB
normal endocrine/exocrine gland phenotype J:82321
n-TUtca2tm1Dhat/n-TUtca2tm1Dhat
Tg(Wap-cre)11738Mam/0
involves: 129 * C57BL/6
normal endocrine/exocrine gland phenotype J:82321
n-TUtca2tm1Mmt/n-TUtca2+
either: B6.129S2-Trnau1tm1Mmt or (involves: 129S2/SvPas * MCH)
no abnormal phenotype detected J:40911
n-TUtca2tm1Mmt/n-TUtca2tm1Mmt
either: B6.129S2-Trnau1tm1Mmt or (involves: 129S2/SvPas * MCH)
embryonic lethality between implantation and somite formation, complete penetrance J:40911
n-TUtca2tm1Mym/n-TUtca2tm1Mym
either: (involves: C57BL/6) or (involves: C57BL/6 * DBA) or (involves: ICR)
abnormal developmental patterning J:97648
decreased embryo size J:97648
embryonic lethality between somite formation and embryo turning, complete penetrance J:97648
n-TUtca2tm2Mym/n-TUtca2tm2.1Mym
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * C57BL/6 * DBA/2
increased apoptosis J:130723
increased cellular sensitivity to oxidative stress J:130723
premature death J:130723

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory