Tigit Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tigit
T cell immunoreceptor with Ig and ITIM domains
MGI:3642260

9 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tigit^{tm1.1(IMPC)Wtsi}/Tigit^{tm1.1(IMPC)Wtsi} C57BL/6N-Tigit^{tm1.1(IMPC)Wtsi}/Wtsi	decreased circulating potassium level	J:211773
	increased circulating free fatty acids level	J:211773
Tigit^tm1Sdl/Tigit^tm1Sdl involves: C57BL/6	abnormal professional antigen presenting cell physiology	J:168902
	decreased interleukin-10 secretion	J:168902
	normal immune system phenotype	J:209990
	increased susceptibility to experimental autoimmune encephalomyelitis	J:168902
	increased T cell proliferation	J:168902
	normal mortality/aging	J:209990
	normal neoplasm	J:209990

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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