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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Mir451a
microRNA 451a
MGI:3619412
24 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Mir144/Mir451atm1.1Mjwe/Mir144/Mir451atm1.1Mjwe
Not Specified
abnormal physiological response to xenobiotic J:163250
anemia J:163250
decreased catalase activity J:163250
decreased hemoglobin content J:163250
decreased mean corpuscular hemoglobin J:163250
decreased mean corpuscular volume J:163250
increased cellular sensitivity to hydrogen peroxide J:163250
increased number of Heinz bodies J:163250
increased red blood cell distribution width J:163250
increased spleen weight J:163250
polychromatophilia J:163250
reticulocytosis J:163250
spleen hyperplasia J:163250
Mir144/Mir451atm1.2Doca/Mir144/Mir451atm1.2Doca
involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ
abnormal erythropoiesis J:163418
anemia J:163418
anisocytosis J:163418
decreased erythrocyte cell number J:163418
decreased hematocrit J:163418
decreased hemoglobin content J:163418
enlarged spleen J:163418
increased erythroid progenitor cell number J:163418
increased red blood cell distribution width J:163418
increased susceptibility to xenobiotic induced morbidity/mortality J:163418
Mir451atm1.2Doca/Mir451atm1.2Doca
involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ
abnormal hematopoietic system morphology/development J:163418
decreased erythrocyte cell number J:163418
decreased hematocrit J:163418
enlarged spleen J:163418
increased erythroid progenitor cell number J:163418
increased red blood cell distribution width J:163418
Mir451atm1Eno/Mir451a+
involves: C57BL/6
abnormal erythrocyte cell number J:163251
Mir451atm1Eno/Mir451atm1Eno
involves: C57BL/6
abnormal fetal derived definitive erythrocyte cell number J:163251
enlarged spleen J:163251
increased erythroid progenitor cell number J:163251
increased physiological sensitivity to xenobiotic J:163251

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/21/2023
MGI 6.22
The Jackson Laboratory