Shank1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Shank1
SH3 and multiple ankyrin repeat domains 1
MGI:3613677

26 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Shank1^em1(IMPC)Mbp/Shank1^em1(IMPC)Mbp C57BL/6N-Shank1^em1(IMPC)Mbp/MbpMmucd	abnormal coat/ hair morphology	J:211773
	abnormal gait	J:211773
	abnormal gallbladder morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	enlarged gallbladder	J:211773
	enlarged ovary	J:211773
	small liver	J:211773
	tremors	J:211773
Shank1^tm1Shng/Shank1^tm1Shng involves: 129S4/SvJae * C57BL/6	abnormal CNS synapse formation	J:132277
	abnormal CNS synaptic transmission	J:132277
	abnormal hippocampus pyramidal cell morphology	J:132277
	abnormal long-term spatial reference memory	J:132277
	abnormal maternal nurturing	J:132277
	abnormal spatial learning	J:132277
	abnormal spatial reference memory	J:132277
	abnormal spatial working memory	J:132277
	decreased locomotor activity	J:132277
	impaired coordination	J:132277
	increased anxiety-related response	J:132277
	normal nervous system phenotype	J:132277
	reduced fertility	J:132277

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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