Akap6 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akap6
A kinase anchor protein 6
MGI:3050566

14 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akap6^tm1.1Mskf/Akap6^tm1.1Mskf A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: C57BL/6 FVB/N * SJL	abnormal heart ventricles weight	J:214288
	cardiac interstitial fibrosis	J:214288
	decreased heart rate	J:214288
	heart left ventricle hypertrophy	J:214288
	increased cardiomyocyte apoptosis	J:214288
	increased heart left atrium weight	J:214288
	increased heart left ventricle wall thickness	J:214288
	increased heart left ventricle weight	J:214288
	increased myocardial fiber size	J:214288
Akap6^tm1.1Mskf/Akap6^tm1.1Mskf Nkx2-5^tm1(cre)Rjs/0 involves: 129S7/SvEvBrd * C57BL/6 * SJL	no abnormal phenotype detected	J:214288
Akap6^tm1.2Mskf/Akap6^tm1.2Mskf involves: BALB/cJ * C57BL/6 * SJL	neonatal lethality	J:214288
Akap6^tm1Jsco/Akap6^tm1Jsco involves: 129 * Black Swiss	abnormal craniofacial morphology	J:121227
	decreased body weight	J:121227
	postnatal lethality, incomplete penetrance	J:121227

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24