Impg2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Impg2
interphotoreceptor matrix proteoglycan 2
MGI:3044955

22 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Impg2^em1(IMPC)Mbp/Impg2^em1(IMPC)Mbp C57BL/6NCrl-Impg2^em1(IMPC)Mbp/MbpMmucd	abnormal coat/ hair morphology	J:211773
	abnormal eye morphology	J:211773
	increased grip strength	J:211773
Impg2^em1Visu/Impg2^em1Visu involves: C57BL/6J * DBA/2	abnormal cone electrophysiology	J:288311
	abnormal ocular fundus morphology	J:288311
	abnormal retina layer morphology	J:288311
	abnormal rod electrophysiology	J:288311
	microgliosis	J:288311
Impg2^em1Xjz/Impg2^em1Xjz C57BL/6J-Impg2^em1Xjz	abnormal extracellular matrix morphology	J:295355
	abnormal retina cone cell morphology	J:295355
	abnormal retina rod cell inner segment morphology	J:295355
	abnormal retina rod cell morphology	J:295355
	astrocytosis	J:295355
	decreased a-wave amplitude	J:295355
	decreased b-wave amplitude	J:295355
	decreased retina cone cell number	J:295355
	impaired autophagy	J:295355
	increased endoplasmic reticulum stress	J:295355
	retina cone cell degeneration	J:295355
	retina degeneration	J:295355
	retina rod cell degeneration	J:295355
	thin retina outer nuclear layer	J:295355
Impg2^em2Xjz/Impg2^em2Xjz C57BL/6J-Impg2^em2Xjz	astrocytosis	J:295355
	retina cone cell degeneration	J:295355
	retina degeneration	J:295355
	retina rod cell degeneration	J:295355
	thin retina outer nuclear layer	J:295355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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