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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Vtcn1
V-set domain containing T cell activation inhibitor 1
MGI:3039619
16 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Vtcn1tm1Lpc/Vtcn1tm1Lpc
B6.129S-Vtcn1tm1Lpc
abnormal myelopoiesis J:145712
decreased susceptibility to bacterial infection J:145712
decreased susceptibility to bacterial infection induced morbidity/mortality J:145712
increased neutrophil cell number J:145712
Vtcn1tm1Mak/Vtcn1tm1Mak
C.Cg-Vtcn1tm1Mak
decreased interleukin-4 secretion J:112130
decreased susceptibility to parasitic infection J:112130
increased interferon-gamma secretion J:112130
Vtcn1tm1Mak/Vtcn1tm1Mak
involves: 129P2/OlaHsd * C57BL/6
no abnormal phenotype detected J:112130
Vtcn1tm1Xxz/Vtcn1tm1Xxz
involves: 129S4/SvJae * BALB/c * C57BL/6
increased CD4-positive, alpha-beta T cell number J:177612
increased circulating glucose level J:177612
increased interleukin-17 secretion J:177612
increased susceptibility to autoimmune diabetes J:177612
increased susceptibility to experimental autoimmune encephalomyelitis J:177612
increased susceptibility to induced morbidity/mortality J:177612
increased T-helper 1 cell number J:177612
increased T-helper 17 cell number J:177612

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory