Fhip2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fhip2b
FHF complex subunit HOOK interacting protein 2B
MGI:3036290

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fhip2b^{em1(IMPC)Ccpcz}/Fhip2b^{em1(IMPC)Ccpcz} C57BL/6N-Fhip2b^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
Fhip2b^em1Wwan/Fhip2b^em1Wwan involves: C57BL/6	abnormal cytokine level	J:285283, J:302658
	abnormal gut flora balance	J:285283
	decreased circulating cholesterol level	J:302658
	decreased circulating LDL cholesterol level	J:302658
	enlarged spleen	J:285283
	hepatic steatosis	J:302658
	increased circulating alanine transaminase level	J:302658
	increased circulating aspartate transaminase level	J:302658
	increased epididymal fat pad weight	J:302658
	increased incidence of tumors by chemical induction	J:285283
	increased leukocyte cell number	J:285283
	increased liver cholesterol level	J:302658
	increased liver triglyceride level	J:302658
	increased liver weight	J:302658
	increased susceptibility to diet-induced obesity	J:302658
	increased susceptibility to induced colitis	J:285283
	liver inflammation	J:302658

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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