Bbs12 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bbs12
Bardet-Biedl syndrome 12
MGI:2686651

30 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bbs12^{em1(IMPC)Ccpcz}/Bbs12⁺ C57BL/6NCrl-Bbs12^{em1(IMPC)Ccpcz}/Ccpcz	abnormal heart morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	enlarged heart	J:211773
	enlarged spleen	J:211773
	enlarged thymus	J:211773
Bbs12^{em1(IMPC)Ccpcz}/Bbs12^{em1(IMPC)Ccpcz} C57BL/6NCrl-Bbs12^{em1(IMPC)Ccpcz}/Ccpcz	no spontaneous movement	J:211773
	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Bbs12^tm1.1Vmar/Bbs12^tm1.1Vmar involves: 129S6/SvEvTac * C57BL/6	abnormal bone marrow morphology	J:189019
	abnormal eating behavior	J:189019
	abnormal fat cell morphology	J:189019
	decreased birth body size	J:189019
	decreased circulating free fatty acids level	J:189019
	decreased circulating interleukin-6 level	J:189019
	decreased circulating tumor necrosis factor level	J:189019
	decreased inflammatory response	J:189019
	increased adipocyte glucose uptake	J:189019
	increased circulating adiponectin level	J:189019
	increased circulating glucose level	J:189019
	increased circulating leptin level	J:189019
	increased epididymal fat pad weight	J:189019
	increased fat cell size	J:189019
	increased insulin sensitivity	J:189019
	increased susceptibility to diet-induced obesity	J:189019
	obese	J:189019
	photoreceptor outer segment degeneration	J:189019
	normal renal/urinary system phenotype	J:189019
	retina degeneration	J:189019
	thin retina outer nuclear layer	J:189019

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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