Asxl3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Asxl3
ASXL transcriptional regulator 3
MGI:2685175

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apcdd1^em1Jlp/Apcdd1⁺ Asxl3^em1Jlp/Asxl3⁺ Mib1^em1Jlp/Mib1⁺ C57BL/6-Apcdd1^em1Jlp Asxl3^em1Jlp Mib1^em1Jlp	dilated heart	J:338889
	increased cardiac output	J:338889
	increased heart left ventricle weight	J:338889
	thin ventricle myocardium compact layer	J:338889
Asxl3^{tm1.1(ASXL3P723R)Clia}/Asxl3^{tm2.1(ASXL3P1817A)Clia} Not Specified	abnormal cardiac muscle tissue morphology	J:322485
	abnormal heart echocardiography feature	J:322485
	abnormal myocardial fiber morphology	J:322485
	abnormal myocardium layer morphology	J:322485
	cardiac fibrosis	J:322485
	decreased cardiac muscle contractility	J:322485
	decreased cardiac output	J:322485
	decreased cardiac stroke volume	J:322485
	myocardium hypertrophy	J:322485

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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