Crb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crb2
crumbs family member 2
MGI:2679260

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Crb1^tm1Wij/Crb1⁺ Crb2^tm1.1Wij/Crb2^tm1.1Wij Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL	abnormal electroretinogram waveform feature	J:207895
	abnormal eye physiology	J:207895
	abnormal retina development	J:207895
	abnormal retina ganglion layer morphology	J:207895
	abnormal retina layer morphology	J:207895
	abnormal retina morphology	J:207895
	abnormal retina outer limiting membrane morphology	J:207895
	abnormal retina photoreceptor layer morphology	J:207895
	decreased retina apoptosis	J:207895
	increased retina apoptosis	J:207895
Crb1^tm1Wij/Crb1^tm1Wij Crb2^tm1.1Wij/Crb2^tm1.1Wij Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL	abnormal electroretinogram waveform feature	J:207895
	abnormal eye physiology	J:207895
	abnormal Muller cell morphology	J:207895
	abnormal retina bipolar cell morphology	J:207895
	abnormal retina layer morphology	J:207895
	abnormal retina morphology	J:207895
	abnormal retina outer limiting membrane morphology	J:207895
	abnormal retina photoreceptor layer morphology	J:207895
	abnormal retina progenitor cell morphology	J:207895
	decreased total retina thickness	J:207895
	disorganized retina layers	J:207895
	increased amacrine cell number	J:207895
	increased retina apoptosis	J:207895
	increased retina rod cell number	J:207895
	increased total retina thickness	J:207895
	retina degeneration	J:207895

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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