Synm Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Synm
synemin, intermediate filament protein
MGI:2661187

47 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Synm^{tm1.1(KOMP)Vlcg}/Synm^{tm1.1(KOMP)Vlcg} C57BL/6N-Synm^{tm1.1(KOMP)Vlcg}/Ucd	abnormal vocalization	J:211773
Synm^{tm1.1(KOMP)Vlcg}/Synm^{tm1.1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal heart echocardiography feature	J:257039
	abnormal heart morphology	J:257039
	abnormal muscle fiber morphology	J:224030
	abnormal muscle morphology	J:224030
	abnormal muscle physiology	J:224030
	abnormal myocardial fiber physiology	J:257039
	abnormal sarcolemma morphology	J:224030
	abnormal skeletal muscle morphology	J:224030
	cardiac fibrosis	J:257039
	cardiac hypertrophy	J:257039
	cardiomyopathy	J:257039
	decreased cardiac output	J:257039
	decreased cardiac stroke volume	J:257039
	decreased heart left ventricle posterior wall thickness	J:257039
	decreased skeletal muscle mass	J:224030
	decreased skeletal muscle size	J:224030
	decreased ventricle muscle contractility	J:257039
	dilated heart left ventricle	J:257039
	heart left ventricle hypertrophy	J:257039
	increased body weight	J:257039
	increased heart rate	J:257039
	increased heart weight	J:257039
	increased muscle fatigability	J:224030
	increased myocardial fiber size	J:257039
	muscle twitch	J:224030
	myocardium hypertrophy	J:257039
	skeletal muscle necrosis	J:224030
Synm^tm1.1Ics/Synm^tm1.1Ics involves: 129S2/SvPas * C57BL/6 * FVB/N * SJL	abnormal muscle electrophysiology	J:268425
	abnormal sarcolemma morphology	J:268425
	abnormal sarcomere morphology	J:268425
	abnormal skeletal muscle fiber morphology	J:268425
	abnormal skeletal muscle fiber type ratio	J:268425
	abnormal skeletal muscle regeneration	J:268425
	centrally nucleated skeletal muscle fibers	J:268425
	hyperactivity	J:268425
	increased basal metabolism	J:268425
	increased body length	J:268425
	increased fluid intake	J:268425
	increased lean body mass	J:268425
	increased oxygen consumption	J:268425
	increased satellite cell number	J:268425
	increased skeletal muscle fiber diameter	J:268425
	increased skeletal muscle mass	J:268425
	increased susceptibility to injury	J:268425
	long tibia	J:268425
	myopathy	J:268425
	skeletal muscle fiber degeneration	J:268425

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23