Plekhg5 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plekhg5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
MGI:2652860

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plekhg5^tm1.1Jbar/Plekhg5^tm1.1Jbar involves: 129S1/Sv * 129X1/SvJ	abnormal angiogenesis	J:155152
	abnormal artery development	J:155152
	abnormal coronary vessel morphology	J:155152
	abnormal kidney vasculature morphology	J:155152
	decreased angiogenesis	J:155152
Plekhg5^tm1Jbar/Plekhg5^tm1Jbar Tg(Tek-cre)1Ywa/0 involves: C57BL/6 * SJL	abnormal blood vessel morphology	J:195233
	abnormal heart left ventricle morphology	J:195233
	abnormal vascular endothelial cell morphology	J:195233
	decreased ventricle muscle contractility	J:195233
	edema	J:195233
	impaired skin barrier function	J:195233
	increased vascular permeability	J:195233

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23