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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tub
TUB bipartite transcription factor
MGI:2651573
43 phenotypes from 3 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tubm1Btlr/Tubm1Btlr
C57BL/6J-Tubm1Btlr
increased body weight J:221485
Tubtm1Rok/Tubtm1Rok
C57BL/6-Tubtm1Rok
decreased retina photoreceptor cell number J:59994
increased retina apoptosis J:59994
increased susceptibility to age related obesity J:59994
increased susceptibility to weight gain J:59994
retina degeneration J:59994
thin retina outer nuclear layer J:59994
Tubtub/Tub+
involves: AKR/J * B6(Cg)-Tubtub/J
normal hearing/vestibular/ear phenotype J:57571
Tubtub/Tubtub
B6(AU)-Tubtub/J
abnormal bony labyrinth J:26067
abnormal ear morphology J:32415
abnormal electroretinogram waveform feature J:121993
abnormal hearing physiology J:32415
abnormal photoreceptor inner segment morphology J:26067
abnormal photoreceptor outer segment morphology J:121993
abnormal retina neuronal layer morphology J:121993
abnormal retina photoreceptor layer morphology J:26067
abnormal retina pigment epithelium morphology J:121993
abnormal retina vasculature morphology J:121993
absent tunnel of Corti J:26067
cochlear ganglion degeneration J:26067
cochlear hair cell degeneration J:26067
cochlear inner hair cell degeneration J:121993
cochlear outer hair cell degeneration J:26067, J:121993
decreased retina photoreceptor cell number J:121993
degeneration of organ of Corti supporting cells J:26067, J:121993
impaired hearing J:32415, J:121993
increased circulating cholesterol level J:18161
increased circulating insulin level J:32415
increased circulating triglyceride level J:18161
increased food intake J:32415
increased or absent threshold for auditory brainstem response J:121993
increased susceptibility to age-related retinal degeneration J:32415, J:121993
obese J:32415
organ of Corti degeneration J:26067
photoreceptor outer segment degeneration J:26067
retina deposits J:121993
retina outer nuclear layer degeneration J:121993
retina photoreceptor degeneration J:121993
Tubtub/Tubtub
C57BL/6J-Tubtub
abnormal Langerhans cell physiology J:13772
enlarged pancreatic islets J:13772
hepatic steatosis J:13772
increased circulating insulin level J:13772
increased liver glycogen level J:13772
increased total body fat amount J:13772
obese J:13772
Tubtub/Tubtub
CAST.B6-Tubtub/Jng
normal hearing/vestibular/ear phenotype J:57571
Tubtub/Tubtub
involves: C57BL/6J
abnormal hypothalamus morphology J:204140

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory