Gars1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gars1
glycyl-tRNA synthetase 1
MGI:2449057

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gars1^C201R/Gars1⁺ Tg(CAG-GARS)DRwb/0 involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N	decreased grip strength	J:179811
	decreased nerve conduction velocity	J:179811
Gars1^C201R/Gars1⁺ Nrcam^m1J/Nrcam^m1J involves: BALB/cAnN * C3H/HeH * C57BL/6J	abnormal axon morphology	J:240096
	abnormal innervation pattern to muscle	J:240096
	abnormal neuromuscular synapse morphology	J:240096
	decreased nerve conduction velocity	J:240096
	impaired coordination	J:240096
	muscle hypoplasia	J:240096
	tremors	J:240096
Gars1^C201R/Gars1⁺ Scn8a^m10J/Scn8a⁺ involves: BALB/cAnN * C3H/HeJ * FVB/NJ	abnormal motor neuron innervation pattern	J:240096
	abnormal neuromuscular synapse morphology	J:240096
	decreased nerve conduction velocity	J:240096
Gars1^C201R/Gars1^C201R Tg(CAG-GARS)DRwb/0 involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N	abnormal axon morphology	J:179811
	abnormal neuromuscular synapse morphology	J:179811
	decreased body weight	J:179811
	decreased nerve conduction velocity	J:179811
	normal mortality/aging	J:179811
	postnatal lethality, complete penetrance	J:179811
Gars1^C201R/Gars1^{Gt(XM256)6Byg} Tg(CAG-GARS)DRwb/0 involves: 129P2/OlaHsd * BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N	abnormal neuromuscular synapse morphology	J:179811
	decreased body weight	J:179811
	decreased nerve conduction velocity	J:179811
	normal mortality/aging	J:179811
	normal nervous system phenotype	J:179811
Gars1^C201R/Gars1^Nmf249 Tg(CAG-GARS)DRwb/0 involves: BALB/cAnN * C3H/HeH * C57BL/6J * FVB/N	abnormal axon morphology	J:179811
	abnormal neuromuscular synapse morphology	J:179811
	decreased body weight	J:179811
	normal mortality/aging	J:179811
Gars1^Nmf249/Gars1⁺ Tg(CAG-GARS)DRwb/0 involves: C57BL/6J * CAST/Ei * FVB/N	abnormal axon morphology	J:179811
	abnormal neuromuscular synapse morphology	J:179811
	decreased body weight	J:179811
	decreased nerve conduction velocity	J:179811
Gars1^Nmf249/Gars1⁺ Scn8a^m10J/Scn8a⁺ involves: C57BL/6J * FVB/NJ	abnormal neuromuscular synapse morphology	J:240096
	decreased nerve conduction velocity	J:240096
	skeletal muscle atrophy	J:240096

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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