Tg(CAG-GARS)DRwb
Transgene Detail

Summary

• Symbol: Tg(CAG-GARS)DRwb
• Name: transgene insertion D, Robert W Burgess
• MGI ID: MGI:5308112
• Synonyms: TgD
• Transgene: Tg(CAG-GARS)DRwb Location: unknown
• Alliance: Tg(CAG-GARS)DRwb page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-GARS)DRwb expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GARS1 (2617)

  Gars1

  (MGI:2449057)

• Mutation details: This transgene consists of the full-length human GARS open reading frame under the control of a CAG promoter consisting of the CMV early enhancer and the chicken beta actin promoter. Two lines were made, line A and D. (J:179811)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:179811 Motley WW, et al., Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels. PLoS Genet. 2011 Dec;7(12):e1002399
• All: 1 reference(s)