Plac8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plac8
placenta-specific 8
MGI:2445289

19 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plac8^{tm1b(EUCOMM)Hmgu}/Plac8^{tm1b(EUCOMM)Hmgu} C57BL/6N-Plac8^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal coat appearance	J:211773
	abnormal lens morphology	J:211773
	abnormal retina morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	persistence of hyaloid vascular system	J:211773
Plac8^tm1Bhk/Plac8⁺ involves: 129S6/SvEvTac * C57BL/6	decreased brown fat lipid droplet number	J:179647
	increased body fat mass	J:179647
	increased body weight	J:179647
	increased brown fat cell lipid droplet size	J:179647
	whitened brown adipose tissue morphology	J:179647
Plac8^tm1Bhk/Plac8^tm1Bhk 129S/SvEv-Plac8^tm1Bhk	abnormal neutrophil physiology	J:145277
	increased leukocyte cell number	J:145277
	increased neutrophil cell number	J:145277
	increased susceptibility to bacterial infection	J:145277
	increased vascular permeability	J:145277
Plac8^tm1Bhk/Plac8^tm1Bhk involves: 129S6/SvEvTac * C57BL/6	abnormal neutrophil physiology	J:145277
	decreased body temperature	J:179647
	decreased brown fat lipid droplet number	J:179647
	impaired adaptive thermogenesis	J:179647
	increased body fat mass	J:179647
	increased body weight	J:179647
	increased brown fat cell lipid droplet size	J:179647
	whitened brown adipose tissue morphology	J:179647

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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