Nlgn3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nlgn3
neuroligin 3
MGI:2444609

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nlgn1^tm1.1Sud/Nlgn1^tm1.1Sud Nlgn2^tm1.1Sud/Nlgn2^tm1.1Sud Nlgn3^tm4.1Sud/Y Tg(Pcp2-cre)2Mpin/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac	abnormal CNS synaptic transmission	J:227671
	abnormal inhibitory postsynaptic currents	J:227671
	abnormal miniature inhibitory postsynaptic currents	J:227671
	abnormal synapse morphology	J:227671
	abnormal synaptic bouton morphology	J:227671
	decreased excitatory postsynaptic current amplitude	J:227671
	decreased miniature inhibitory postsynaptic current amplitude	J:227671
	decreased miniature inhibitory postsynaptic current frequency	J:227671
Nlgn1^tm1.1Sud/Nlgn1^tm1.1Sud Nlgn3^tm4.1Sud/Y Tg(Pcp2-cre)2Mpin/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac	abnormal synapse morphology	J:227671
	decreased excitatory postsynaptic current amplitude	J:227671
	normal nervous system phenotype	J:227671
Nlgn1^tm1Bros/Nlgn1^tm1Bros Nlgn2^tm1Bros/Nlgn2^tm1Bros Nlgn3^tm1Bros/Nlgn3^tm1Bros Not Specified	abnormal nervous system development	J:113647
	abnormal pre-Botzinger complex physiology	J:113647
	abnormal respiration	J:113647
	decreased body weight	J:113647
	neonatal lethality, complete penetrance	J:113647
Nlgn1^tm1Bros/Nlgn1^tm1Bros Nlgn3^tm1Bros/Nlgn3^tm1Bros Not Specified	abnormal CNS synaptic transmission	J:113647
	abnormal parental behavior	J:113647
	reduced fertility	J:113647
Nlgn2^tm1.1Sud/Nlgn2^tm1.1Sud Nlgn3^tm4.1Sud/Y Tg(Pcp2-cre)2Mpin/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac	abnormal miniature inhibitory postsynaptic currents	J:227671
	abnormal synapse morphology	J:227671
	decreased excitatory postsynaptic current amplitude	J:227671
	decreased miniature inhibitory postsynaptic current amplitude	J:227671
	decreased miniature inhibitory postsynaptic current frequency	J:227671
	normal nervous system phenotype	J:227671
Nlgn2^tm1Bros/Nlgn2^tm1Bros Nlgn3^tm1Bros/Nlgn3^tm1Bros Not Specified	abnormal CNS synaptic transmission	J:113647
	abnormal parental behavior	J:113647
	reduced fertility	J:113647

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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