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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Frem2
Fras1 related extracellular matrix protein 2
MGI:2444465
60 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Frem2b2b1562Clo/Frem2b2b1562Clo
C57BL/6J-Frem2b2b1562Clo 		absent kidney J:175213
cryptophthalmos J:175213
polydactyly J:175213
syndactyly J:175213
Frem2b2b3270Clo/Frem2b2b3270Clo
C57BL/6J-Frem2b2b3270Clo 		anophthalmia J:175213
diaphragmatic hernia J:175213
microphthalmia J:175213
right aortic arch J:175213
Frem2em1Hali/Frem2em2Hali
C57BL/6J-Frem2em1Hali Frem2em2Hali 		abnormal anterior eye segment morphology J:279933
abnormal cornea morphology J:279933
abnormal eye morphology J:279933
abnormal lens morphology J:279933
absent ciliary body J:279933
acoria J:279933
cornea vascularization J:279933
cryptophthalmos J:279933
increased total retina thickness J:279933
iris hypoplasia J:279933
iris synechia J:279933
single kidney J:279933
syndactyly J:279933
Frem2em2Hali/Frem2em2Hali
C57BL/6J-Frem2em2Hali 		cryptophthalmos J:279933
normal limbs/digits/tail phenotype J:279933
single kidney J:279933
Frem2Gt(KST252)Byg/Frem2my-Ucl
involves: 129P2/OlaHsd * CD-1 * NMRI 		bleb J:98344
Frem2my-F11/Frem2my-F11
either: (involves: C3HeB/FeJ * C57BL/6J) or (involves: C3HeB/FeJ * C57BL/6J * M. m. castaneus) 		abnormal coat/hair pigmentation J:101189
abnormal digit morphology J:101189
abnormal head morphology J:101189
abnormal heart valve morphology J:101189
abnormal limb morphology J:101189
abnormal lung morphology J:101189
absent outer ear J:101189
anophthalmia J:101189
atrial septal defect J:101189
decreased birth weight J:101189
hemorrhage J:101189
microphthalmia J:101189
neonatal lethality, incomplete penetrance J:101189
oligodactyly J:101189
open neural tube J:101189
small ears J:101189
sparse hair J:101189
syndactyly J:101189
variable body spotting J:101189
Frem2my-Ucl/Frem2my-Ucl
involves: NMRI 		cryptophthalmos J:98344
fetal bleb J:98344
prenatal lethality, incomplete penetrance J:98344
syndactyly J:98344
Frem2my/Frem2my
involves: MY/HuLeJ * C57BL/6 		absent kidney J:111788
bleb J:111788
cryptophthalmos J:111788
syndactyly J:111788
Frem2my/Frem2my
Not Specified 		abnormal craniofacial development J:14847
abnormal embryo development J:20762
abnormal eye development J:14847, J:20762
abnormal facial morphology J:14847
abnormal limb morphology J:14847
abnormal skin morphology J:20762
absent kidney J:20762
acrania J:20762
bleb J:14847
clubfoot J:20762
eye bleb J:14847
hydrocephaly J:14847
meroanencephaly J:20762
perinatal lethality, incomplete penetrance J:14847
preaxial polydactyly J:20762
short face J:14847
short snout J:14847
syndactyly J:20762
Frem2ne/Frem2ne
STOCK Frem2ne/GrsrJ 		abnormal ear shape J:136583
abnormal eyelid morphology J:136583
normal cardiovascular system phenotype J:136583
cryptophthalmos J:136583
decreased litter size J:136583
fused phalanges J:136583
irregular coat pigmentation J:136583
microphthalmia J:136583
normal renal/urinary system phenotype J:136583
syndactyly J:136583
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory