Pgap3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pgap3
post-GPI attachment to proteins 3
MGI:2444461

21 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pgap3^tm1.1Ymra/Pgap3^tm1.1Ymra B6.Cg-Pgap3^tm1.1Ymra	abnormal T-helper 2 cell differentiation	J:203443
	decreased B cell proliferation	J:203443
	normal immune system phenotype	J:203443
	impaired macrophage phagocytosis	J:203443
	increased anti-double stranded DNA antibody level	J:203443
	increased anti-single stranded DNA antibody level	J:203443
	increased spleen germinal center number	J:203443
	renal glomerulus hypertrophy	J:203443
Pgap3^tm1.1Ymra/Pgap3^tm1.1Ymra involves: 129 * C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:181221
	abnormal head size	J:181221
	abnormal T cell morphology	J:181221
	abnormal tail morphology	J:181221
	decreased T cell proliferation	J:181221
	normal immune system phenotype	J:181221
	increased susceptibility to experimental autoimmune encephalomyelitis	J:181221
	increased susceptibility to induced morbidity/mortality	J:181221
	increased T cell proliferation	J:181221
	kinked tail	J:181221
	limb grasping	J:181221
	paralysis	J:181221
	postnatal growth retardation	J:181221
	normal reproductive system phenotype	J:181221
Pgap3^tm1Ymra/Pgap3^tm1Ymra Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd	normal immune system phenotype	J:203443
Pgap3^tm1Ymra/Pgap3^tm1Ymra Tg(Lck-cre)#Jxm/0 involves: C57BL/6 * CBA	normal immune system phenotype	J:203443

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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