Lrig3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrig3
leucine-rich repeats and immunoglobulin-like domains 3
MGI:2443955

41 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrig3^{em1(IMPC)Ccpcz}/Lrig3^{em1(IMPC)Ccpcz} C57BL/6NCrl-Lrig3^{em1(IMPC)Ccpcz}/Ccpcz	abnormal caudal vertebrae morphology	J:211773
	abnormal cranium morphology	J:211773
	abnormal digit morphology	J:211773
	abnormal gait	J:211773
	abnormal heart left ventricle morphology	J:211773
	abnormal heart morphology	J:211773
	abnormal skeletal muscle morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal thymus morphology	J:211773
	abnormal vertebrae morphology	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased body weight	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	enlarged heart	J:211773
	enlarged thymus	J:211773
	female infertility	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating creatine kinase level	J:211773
	increased circulating lactate dehydrogenase level	J:211773
	increased kidney weight	J:211773
	male infertility	J:211773
Lrig3^{Gt(LST016)Byg}/Lrig3^{Gt(LST016)Byg} B6.129P2-Lrig3^{Gt(LST016)Byg}	abnormal craniofacial morphology	J:142510
	abnormal ear development	J:142510
	abnormal lateral semicircular canal morphology	J:142510
	circling	J:142510
	decreased lateral semicircular canal size	J:142510
	head tossing	J:142510
	normal hearing/vestibular/ear phenotype	J:142510
	short snout	J:142510
Lrig3^tm1.1Good/Lrig3^tm1.1Good B6N.Cg-Lrig3^tm1.1Good	abnormal lateral semicircular canal morphology	J:202451
Lrig3^tm1.1Good/Lrig3^tm1.1Good B6N.Cg-Lrig3^tm1.1Good	decreased posterior semicircular canal size	J:202451
Lrig3^tm1.1Good/Lrig3^tm1.1Good involves: BALB/cJ	abnormal craniofacial morphology	J:142510
Lrig3^tm1.1Good/Lrig3^tm1.1Good involves: BALB/cJ	abnormal lateral semicircular canal morphology	J:142510
Lrig3^tm1.1Hhed/Lrig3^tm1.1Hhed B6.129(Cg)-Lrig3^tm1.1Hhed	abnormal heart left ventricle morphology	J:242435
	abnormal heart left ventricle weight	J:242435
	decreased body size	J:242435
	decreased body weight	J:242435
	decreased cardiac output	J:242435
	decreased cardiac stroke volume	J:242435
	decreased circulating glycerol level	J:242435
	decreased circulating HDL cholesterol level	J:242435
	decreased circulating insulin level	J:242435
	increased heart rate	J:242435
	increased systemic arterial blood pressure	J:242435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23