Snx8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Snx8
sorting nexin 8
MGI:2443816

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Snx8^tm1Hbsh/Snx8^tm1Hbsh Not Specified	abnormal chemokine secretion	J:254306
	abnormal circulating chemokine level	J:254306
	abnormal dendritic cell physiology	J:254306
	abnormal macrophage physiology	J:254306
	decreased circulating CXCL10 level	J:254306
	decreased circulating tumor necrosis factor level	J:254306
	decreased CXCL10 secretion	J:254306
	decreased macrophage cytokine production	J:254306
	normal immune system phenotype	J:254306
	increased susceptibility to bacterial infection	J:254306
	increased susceptibility to bacterial infection induced morbidity/mortality	J:254306
Snx8^{tm2a(EUCOMM)Hmgu}/Snx8^{tm2a(EUCOMM)Hmgu} C57BL/6N-Snx8^{tm2a(EUCOMM)Hmgu}/Wtsi	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating fructosamine level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
	increased leukocyte cell number	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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