Cnot6l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cnot6l
CCR4-NOT transcription complex, subunit 6-like
MGI:2443154

31 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cnot6l^{tm1b(EUCOMM)Wtsi}/Cnot6l^{tm1b(EUCOMM)Wtsi} C57BL/6NCrl-Cnot6l^{tm1b(EUCOMM)Wtsi}/Ieg	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal optic disk morphology	J:211773
	decreased locomotor activity	J:211773
	decreased startle reflex	J:211773
	enlarged spleen	J:211773
	hyperactivity	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased heart weight	J:211773
	increased mean platelet volume	J:211773
	increased vertical activity	J:211773
	thin ventricular wall	J:211773
	tremors	J:211773
Cnot6l^tm1Tya/Cnot6l^tm1Tya B6.Cg-Cnot6l^tm1Tya	abnormal circulating glucose level	J:274297
	abnormal circulating insulin level	J:274297
	abnormal circulating lipid level	J:274297
	abnormal homeostasis	J:274297
	normal behavior/neurological phenotype	J:274297
	decreased brown adipose tissue amount	J:274297
	decreased brown fat cell size	J:274297
	decreased liver weight	J:274297
	decreased respiratory quotient	J:274297
	decreased subcutaneous adipose tissue amount	J:274297
	decreased susceptibility to diet-induced hepatic steatosis	J:274297
	decreased susceptibility to diet-induced obesity	J:274297
	decreased white adipose tissue amount	J:274297
	increased basal metabolism	J:274297
	increased circulating ketone body level	J:274297
	increased lean body mass	J:274297
	increased oxygen consumption	J:274297
	normal skeleton phenotype	J:274297

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/20/2026 MGI 6.24