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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Arhgef9
CDC42 guanine nucleotide exchange factor 9
MGI:2442233
26 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arhgef9em1Frk/Y
C57BL/6NJ-Arhgef9em1Frk/FrkJ 		abnormal excitatory synapse morphology J:364541
abnormal hippocampal pyramidal neuron dendrite morphology J:364541
abnormal hippocampus neuron morphology J:364541
abnormal hippocampus physiology J:364541
abnormal interictal brain wave pattern J:364541
abnormal postsynaptic density morphology J:364541
absence seizures J:364541
decreased miniature inhibitory postsynaptic current amplitude J:364541
hyperekplexia J:364541
impaired ability to fire action potentials J:364541
increased miniature excitatory postsynaptic current amplitude J:364541
myoclonus J:364541
reduced sensorimotor gating J:364541
seizures J:364541
tonic seizures J:364541
tonic-clonic seizures J:364541
Arhgef9tm1.1Betz/Y
B6.129P2-Arhgef9tm1.1Betz 		abnormal excitatory postsynaptic potential J:124926
abnormal inhibitory postsynaptic currents J:124926
abnormal neuron morphology J:124926
abnormal spatial learning J:124926
abnormal synaptic plasticity J:124926
decreased exploration in new environment J:124926
enhanced long-term potentiation J:124926
increased anxiety-related response J:124926
increased thigmotaxis J:124926
reduced long-term depression J:124926
Arhgef9tm1Betz/Y
Emx1tm1(cre)Yql/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		abnormal neuron morphology J:141850
Arhgef9tm1Betz/Y
Tg(Camk2a-cre)2834Lusc/0
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal neuron morphology J:141850
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory