Ffar2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ffar2
free fatty acid receptor 2
MGI:2441731

33 phenotypes from 7 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ffar2^{tm1b(EUCOMM)Hmgu}/Ffar2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Ffar2^{tm1b(EUCOMM)Hmgu}/J	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
Ffar2^tm1Dgen/Ffar2^tm1Dgen involves: C57BL/6	abnormal granulocyte physiology	J:153951
	abnormal neutrophil physiology	J:153951
	impaired neutrophil chemotaxis	J:153951
	impaired neutrophil phagocytosis	J:153951
	increased susceptibility to induced arthritis	J:153951
	increased susceptibility to induced colitis	J:153951
	increased susceptibility to xenobiotic induced morbidity/mortality	J:153951
	increased T cell number	J:153951
	lung inflammation	J:153951
Ffar2^tm1Fmgb/Ffar2^tm1Fmgb involves: 129S/SvEv	abnormal intestine physiology	J:191508
	decreased circulating insulin level	J:191508
	normal homeostasis/metabolism phenotype	J:191508
	impaired glucose tolerance	J:191508
Ffar2^tm1Gzt/Ffar2^tm1Gzt involves: C57BL/6	normal cardiovascular system phenotype	J:172798
Ffar2^tm1Lex/Ffar2^tm1Lex involves: 129S/SvEvBrd * C57BL/6J	abnormal circulating free fatty acids level	J:138134
Ffar2^tm1Soff/Ffar2^tm1Soff B6.129-Ffar2^tm1Soff	normal endocrine/exocrine gland phenotype	J:227939
	normal homeostasis/metabolism phenotype	J:227939
	increased circulating insulin level	J:227939
Ffar2^tm2Lex/Ffar2^tm2Lex involves: 129S7/SvEvBrd * C57BL/6	abnormal colon morphology	J:157383
	abnormal cytokine level	J:157383
	abnormal defecation	J:157383
	abnormal inflammatory response	J:157383
	abnormal neutrophil morphology	J:157383
	decreased body weight	J:157383
	decreased circulating tumor necrosis factor level	J:157383
	decreased susceptibility to induced colitis	J:157383
	decreased tumor necrosis factor secretion	J:157383
	impaired neutrophil chemotaxis	J:157383
	increased body weight	J:157383
	increased circulating tumor necrosis factor level	J:157383
	increased susceptibility to xenobiotic induced morbidity/mortality	J:157383
	large intestinal inflammation	J:157383
	rectal hemorrhage	J:157383
	sepsis	J:157383

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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