43 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nod2em1(IMPC)Mbp/Nod2em1(IMPC)Mbp C57BL/6N-Nod2em1(IMPC)Mbp/MbpMmucd	abnormal lymph node morphology	J:211773
	abnormal pancreas morphology	J:211773
	abnormal testis morphology	J:211773
	decreased anxiety-related response	J:211773
	decreased thigmotaxis	J:211773
	enlarged lymph nodes	J:211773
	hyperactivity	J:211773
Nod2tm1Daph/Nod2tm1Daph involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal autophagy	J:157879
	abnormal macrophage physiology	J:157879
Nod2tm1Flv/Nod2tm1Flv C.129S1-Nod2tm1Flv	decreased susceptibility to induced arthritis	J:178054
Nod2tm1Flv/Nod2tm1Flv involves: 129S1/Sv	abnormal response to infection	J:147177
	abnormal T-helper 1 physiology	J:147177
	impaired macrophage phagocytosis	J:147177
	impaired neutrophil phagocytosis	J:147177
	increased circulating interferon-gamma level	J:147177
	increased circulating interleukin-2 level	J:147177
	increased circulating tumor necrosis factor level	J:147177
	increased leukocyte cell number	J:147177
	increased neutrophil cell number	J:147177
	increased susceptibility to bacterial infection induced morbidity/mortality	J:147177
Nod2tm1Flv/Nod2tm1Flv involves: 129S1/Sv * C57BL/6	abnormal macrophage physiology	J:96035, J:132126
	abnormal susceptibility to infection	J:96035
	decreased IgG level	J:96035
	decreased interleukin-6 secretion	J:132126
	decreased susceptibility to endotoxin shock	J:96035
	decreased tumor necrosis factor secretion	J:132126
Nod2tm1Jhgt/Nod2tm1Jhgt B6.Cg-Nod2tm1Jhgt	abnormal cytokine level	J:124575
	abnormal immune system morphology	J:124575
	abnormal immune system physiology	J:124575
	abnormal interferon level	J:124575
	abnormal interleukin level	J:124575
	abnormal lymph node B cell domain morphology	J:124575
	abnormal Peyer's patch morphology	J:124575
	abnormal response to infection	J:124575
	abnormal tumor necrosis factor level	J:124575
	enlarged Peyer's patches	J:124575
	increased CD4-positive, alpha-beta T cell number	J:124575
	increased double-negative T cell number	J:124575
	increased Peyer's patch number	J:124575
	increased susceptibility to induced colitis	J:124575
Nod2tm1Mka/Nod2tm1Mka involves: C57BL/6	abnormal cytokine level	J:96128
	abnormal macrophage morphology	J:96128
	increased interleukin-1 beta secretion	J:96128
	increased susceptibility to induced colitis	J:96128
	increased susceptibility to xenobiotic induced morbidity/mortality	J:96128
	weight loss	J:96128
Nod2tm1Pmu/Nod2tm1Pmu involves: BALB/c * C57BL/6	abnormal macrophage physiology	J:86264
	decreased susceptibility to endotoxin shock	J:86264
Nod2tm1Vmd/Nod2tm1Vmd B6.129-Nod2tm1Vmd	abnormal cytokine secretion	J:106976