Brcc3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Brcc3
BRCA1/BRCA2-containing complex, subunit 3
MGI:2389572

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brcc3^{em1(IMPC)Wtsi}/Brcc3^{em1(IMPC)Wtsi} C57BL/6N-Brcc3^{em1(IMPC)Wtsi}/WtsiCnrm	thrombocytosis	J:211773
Brcc3^em1Bcgen/Brcc3^em1Bcgen C57BL/6J-Brcc3^em1Bcgen	abnormal interleukin-1 beta secretion	J:363478
	abnormal macrophage physiology	J:277205
	decreased circulating interleukin-1 beta level	J:277205
	decreased inflammatory response	J:277205
	decreased interleukin-1 beta secretion	J:277205
	decreased susceptibility to endotoxin shock	J:277205
	normal mortality/aging	J:277205

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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