Lnpep Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lnpep
leucyl/cystinyl aminopeptidase
MGI:2387123

27 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lnpep^tm1.1Sych/Lnpep^tm1.1Sych involves: BALB/cJ * C57BL/6	abnormal spatial working memory	J:154386
	normal behavior/neurological phenotype	J:154386
	impaired coordination	J:154386
Lnpep^{tm1b(KOMP)Wtsi}/Lnpep^{tm1b(KOMP)Wtsi} C57BL/6N-Lnpep^{tm1b(KOMP)Wtsi}/Tcp	abnormal behavior	J:211773
	abnormal seminal vesicle morphology	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased vertical activity	J:211773
	increased anxiety-related response	J:211773
	increased thigmotaxis	J:211773
Lnpep^tm1Ske/Lnpep^tm1Ske B6.129S-Lnpep^tm1Ske	decreased brown adipose tissue amount	J:220356
	decreased circulating adiponectin level	J:220356
	decreased circulating cholesterol level	J:220356
	decreased susceptibility to diet-induced obesity	J:220356
	decreased total body fat amount	J:220356
	decreased white fat cell lipid droplet size	J:220356
	decreased white fat cell size	J:220356
	normal growth/size/body region phenotype	J:220356
	normal homeostasis/metabolism phenotype	J:220356
	improved glucose tolerance	J:220356
	increased circulating leptin level	J:220356
	increased core body temperature	J:220356
	increased insulin sensitivity	J:220356
	increased oxygen consumption	J:220356
Lnpep^tm1Ske/Lnpep^tm1Ske involves: 129S/SvEv * Black Swiss	abnormal glucose homeostasis	J:76570
	enlarged heart	J:76570
	insulin resistance	J:76570

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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