About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ncoa5
nuclear receptor coactivator 5
MGI:2385165
35 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Ncoa5tm1.1(KOMP)Mbp/Ncoa5+
C57BL/6N-Ncoa5tm1.1(KOMP)Mbp/Tcp
abnormal heart morphology J:211773
enlarged heart J:211773
hydrometra J:211773
increased eosinophil cell number J:211773
increased heart weight J:211773
small superior vagus ganglion J:211773
Ncoa5tm1.1(KOMP)Mbp/Ncoa5tm1.1(KOMP)Mbp
C57BL/6N-Ncoa5tm1.1(KOMP)Mbp/Tcp
embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
preweaning lethality, complete penetrance J:211773
Ncoa5tm1Hxia/Ncoa5+
C.129(B6)-Ncoa5tm1Hxia
impaired glucose tolerance J:207622
increased fasting circulating glucose level J:207622
increased hepatocellular carcinoma incidence J:207622
Ncoa5tm1Hxia/Ncoa5+
involves: 129 * C57BL/6
abnormal circulating protein level J:207622
abnormal epididymis physiology J:284227
abnormal liver morphology J:207622
abnormal sperm head morphology J:284227
abnormal sperm midpiece morphology J:284227
abnormal sperm mitochondrial sheath morphology J:284227
asthenozoospermia J:284227
chronic liver inflammation J:207622
decreased pancreatic islet number J:207622
decreased sperm progressive motility J:284227
hepatic steatosis J:207622
normal homeostasis/metabolism phenotype J:207622
impaired glucose tolerance J:207622
increased circulating alanine transaminase level J:207622
increased fasting circulating glucose level J:207622
increased hepatocellular carcinoma incidence J:207622
increased hepatocyte apoptosis J:207622
increased hepatocyte proliferation J:207622
increased liver triglyceride level J:207622
insulin resistance J:207622
liver fibrosis J:207622
male infertility J:207622, J:284227
reduced male fertility J:284227
normal reproductive system phenotype J:207622
small pancreatic islets J:207622
teratozoospermia J:284227

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory