Mrtfa Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrtfa
myocardin related transcription factor A
MGI:2384495

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mamstr^tm1.2Eno/Mamstr^tm1.2Eno Mrtfa^tm1Eno/Mrtfa^tm1Eno involves: 129 * C57BL/6	abnormal muscle physiology	J:179880
	abnormal skeletal muscle satellite cell proliferation	J:179880
	cachexia	J:179880
	decreased body weight	J:179880
	decreased skeletal muscle weight	J:179880
	impaired skeletal muscle regeneration	J:179880
	muscular atrophy	J:179880
	perinatal lethality, incomplete penetrance	J:179880
Mrtfa^tm1Eno/Mrtfa^tm1Eno Mrtfb^tm2.1Eno/Mrtfb^tm2.1Eno Tg(GFAP-cre)25Mes/0 involves: 129 * 129S/SvEv * C57BL/6 * FVB/N	abnormal dentate gyrus morphology	J:161853
	abnormal hippocampus morphology	J:161853
	abnormal hippocampus neuron morphology	J:161853
	abnormal hippocampus pyramidal cell layer	J:161853
	abnormal neuron differentiation	J:161853
	abnormal neuronal migration	J:161853
	abnormal olfactory bulb morphology	J:161853
	abnormal postnatal subventricular zone morphology	J:161853
	abnormal rostral migratory stream morphology	J:161853
	absent anterior commissure	J:161853
	absent corpus callosum	J:161853
	decreased body weight	J:161853
	decreased striatum size	J:161853
	impaired fibroblast cell migration	J:161853
	increased neuron apoptosis	J:161853
	postnatal lethality, complete penetrance	J:161853

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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