Ackr4 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ackr4
atypical chemokine receptor 4
MGI:2181676

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ackr4^tm1.1Rjbn/Ackr4^tm1.1Rjbn B6.129S6-Ackr4^tm1.1Rjbn	abnormal CD4-positive, alpha-beta T cell number	J:166490
	abnormal CD4-positive, alpha-beta T cell physiology	J:166490
	abnormal chemokine level	J:166490
	abnormal circulating chemokine level	J:166490
	abnormal T-helper 17 cell differentiation	J:166490
	decreased T cell proliferation	J:166490
	increased interleukin-23 secretion	J:166490
	increased susceptibility to experimental autoimmune encephalomyelitis	J:166490
	increased T-helper 17 cell number	J:166490
	spleen hyperplasia	J:166490
Ackr4^tm1Ccbl/Ackr4⁺ involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:182799
Ackr4^tm1Dgen/Ackr4^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:101679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23