Rac3 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rac3
Rac family small GTPase 3
MGI:2180784

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^tm1Tno/Apc⁺ Rac3^tm1.1Bea/Rac3^tm1.1Bea Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2	abnormal tumor susceptibility	J:306088
	decreased alimentary system tumor incidence	J:306088
	decreased intestinal adenoma incidence	J:306088
	decreased tumor cell proliferation	J:306088
Rac3^tm1Hkp/Rac3^tm1Hkp Tg(BCR/ABL)623Hkp/0 involves: C57BL/6 * C57BL/6J * CBA	increased leukemia incidence	J:99168
	premature death	J:99168

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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